Must Read: Too Much Sugar Intake Could Lead To Alzheimer's Disease, New Study Suggests
Researchers from the University of Bath found that a diet containing too much sugar could cause Alzheimer's. An elevated blood-sugar level enables this neurological illness to develop.
The new study supplements past research that presented diabetic people of having a high risk of developing Alzheimer’s, Metro reported. However, the new research now introduced that even non-diabetic individuals who consume foods rich in sugar are at risk of this neurological disorder. This indicates that the enzyme protecting the body from developing Alzheimer’s is badly affected by consuming such foods.
According to Mail Online, extremely high level of blood-glucose impedes the function of a significant protein, which normally prevents brain inflammation linked with dementia. Though former studies displayed that diabetes could increase the risk of developing Alzheimer's disorder and vascular dementia. The new study had the first solid proof to clarify why abnormally high blood sugar levels, or hyperglycemia, affect conscious performance.
"Excess sugar is well known to be bad for us when it comes to diabetes and obesity, but this potential link with Alzheimer's disease is yet another reason that we should be controlling our sugar intake in our diets," Dr Omar Kassaar from the University of Bath said.
In Alzheimer's, abnormal proteins accumulate to build plaques forming coils in the brain. As a result, the brain will be successively harmed resulting in an extreme cognitive deterioration.
To gather evidence, scientists used brain samples of 30 participants with and without Alzheimer's. They then tested them for protein glycation, which is an alteration brought about by high levels of blood glucose.
From their experiment, the initial phases of Alzheimer's glycation impaired an enzyme called MIF (macrophage migration inhibitory factor) which functions for immune response and insulin regulation.
Furthermore, MIF participates in the reaction of brain cells called glia to the formation of abnormal proteins within the brain during Alzheimer's disease. This exhibits that as Alzheimer's progresses, glycation of these enzymes rises as well.